What effect does the administration of fentanyl on induction have on the oxyhemoglobin dissociation curve?

The administration of fentanyl during induction may lead to a rightward shift in the oxyhemoglobin dissociation curve. This shift indicates a decreased affinity of hemoglobin for oxygen, which means that oxygen is more readily released to the tissues.

Several factors contribute to this phenomenon. Fentanyl, as an opioid analgesic, can induce respiratory depression, leading to hypoventilation and decreased arterial blood oxygen levels. In such circumstances, the body may respond by facilitating oxygen delivery to tissues that are in greater need of oxygen, which is reflected in the rightward shift of the curve.

Additionally, the metabolic effects of high levels of carbon dioxide (hypercapnia) and lower pH (acidosis) that may occur with respiratory depression can also influence the oxyhemoglobin dissociation curve, promoting the release of oxygen from hemoglobin.

Thus, the correct choice reflects the physiological changes that occur due to fentanyl's effects on respiration and tissue oxygen dynamics.