After an unsuccessful first intubation attempt in a patient with multiple comorbid conditions, what should be the next step according to the ASA Difficult Airway algorithm?

According to the ASA Difficult Airway Algorithm, if the first intubation attempt fails, the next appropriate step is to assess the situation and ensure adequate resources are available. Calling for help is crucial, especially in complex cases where the patient has multiple comorbid conditions that may complicate airway management.

Involving additional personnel can provide extra expertise and assist in securing the airway safely. This step is particularly important as it may necessitate the involvement of experienced practitioners who can offer alternative strategies or assist with more advanced airway management techniques.

Subsequently, after securing help, the next options can be considered, including reassessing the ability to ventilate with a bag-mask device or using alternative airway devices. However, these actions come after ensuring that adequate assistance is on standby, which emphasizes the importance of teamwork and safety in airway management.